"One of the main effects of hitting the wall is emotional. People may lose their sense of drive and suddenly feel depressed. They may also suffer from a general sense of confusion, and they may have trouble thinking clearly about what they are trying to do. Some experts think that these mental effects are caused by an overabundance of serotonin in the brain, which seems to be a common effect of running out of carbohydrate energy."
"Another contributing factor that may cause people to hit the wall could be insufficient hydration. The body generally needs water to perform most activities, and any kind of endurance-based sport will often cause as lot of sweating, especially if the temperature is high. Sometimes athletes may not hydrate themselves sufficiently before undertaking an activity, and as a result, they might hit the wall faster than they normally would."
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wise GEEK clear answers from common questions
'What does 'Hitting The Wall' mean?
http://www.wisegeek.com/what-does-hitting-the-wall-mean.htm
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